It is mentioned that the first settlement in the Sanctuary of Apollo Simintheus in Gülpınar Town of Ayvacık district dates back to the 5th millennium BC. In addition, Smintheion in this area is dedicated to Apollo, the master of mice. It is stated that it is a sanctuary dedicated to the God Apollo to protect the farmlands and grain storehouses from the invasion of mice and to protect them from the plague germs carried by the mice, after settling into agriculture and starting to the agriculture process. In the area, there are many historical buildings such as temples, prehistoric ruins, bathhouses and ceremonial road. Even if you are interested in history or just love to visit, you should not forget that Apollo Simintheus is a place for a must-visit.